| 货号 | AF620-SP |
| 别名 | HHV5wtgp117; vCXC1; vCXCL1; Y18 | 全称 | Cytomegalovirus UL146 |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects viral CMV UL146/vCXC1 in direct ELISAs and Western blots. |
| 使用方法 | Western Blot: 0.1 µg/mL Neutralization: Measured by its ability to neutralize CMV UL146/vCXC1-induced chemotaxis in the BaF3 mouse pro‑B cell line transfected with human CXCR2. The Neutralization Dose (ND50) is typically 10-30 µg/mL in the presence of 0.3 µg/mL Recombinant Viral CMV UL146/vCXC1. |
| 来源 | Polyclonal Goat IgG |
| 产品组分 |
| 供应商 | R&D Systems |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant viral CMV UL146/vCXC1 |
| 内毒素水平 | <0.10 EU per 1 μg of the antibody by the LAL method. |
| 生物活性 | Viral |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Cytomegalovirus (CMV), a member of the beta herpesvirus subfamily, typically causes subclinical or latent infections in the normal adult population. However, CMV can cause congenital disease during pregnancy and is a human opportunistic pathogen that affects immunocompromised individuals. Virulent CMV clinical isolates have also been shown to carry at least 19 genes, designated UL133 - UL151, that are not found in laboratory strains that have lost virulence characteristics. Two of these genes, UL146 and UL147, exhibit sequence similarity to CXC chemokines. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
|
Chemotaxis Induced by CMV UL146/vCXC1 and Neutralization by CMV UL146/vCXC1 Antibody. Recombinant Viral CMV UL146/ |
