| 货号 | AF6905-SP |
| 别名 | Alpha 2,3-ST 1; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; DKFZp666E036; DKFZp779K2051; EC 2.4.99; EC 2.4.99.4; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; Gal-NAc6S; sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase); sialyltransferase 4A (beta-galactoside alpha-2,3-sialyltransferase); sialyltransferase 4A (beta-galactoside alpha-2,3-sialytransferase); Sialyltransferase 4A; SIAT4; SIAT4A; SIAT4-A; SIATFL; SIATFLFLJ36548; ST3 beta-galactoside alpha-2,3-sialyltransferase 1; ST3Gal I; ST3GalA; ST3GalA.1MGC9183; ST3GalI; ST3GalIA; ST3GalIA1,Beta-galactoside alpha-2,3-sialyltransferase 1; ST3O; ST3OST3GalA | 全称 | ST3 beta-Galactoside alpha-2,3-Sialyltransferase 1 |
| 反应种属 | Human |
| 应用 | Western Blot(1 µg/mL) |
| 目标/特异性 | Detects human ST3 beta -Gal alpha -2,3-Sialyltransferase 1/ST3GAL1 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross‑reactivity with recombinant human ST3GAL2 is observed. |
| 使用方法 | Western Blot: 1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 6482 (Human); 20442 (Mouse); 362924 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | human ST3 beta -Gal alpha -2,3-Sialyltransferase 1/ST3GAL1 Accession # Q11201 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | ST3 beta -Gal alpha -2,3-Sialyltransferase 1 (ST3GAL1, also known asSIAT4 and SIAT4A) is a 45 kDa member of glycosyltransferase family 29 thatcatalyzes the transfer of sialic acid from CMP-sialic acid togalactose-containing substrates. The full length ST3GAL1is a type II Golgimembrane glycoprotein that can be proteolytically processed to a soluble form.ST3Gal1 contributes to the alpha2-3-sialylation of O-glycans such as Tantigens. Upon maturation of Dendritic cells derived from monocytes ST3GAl1 isaltered in a stimulus-dependent manner. Multiple isoforms of human ST3GAL1 havebeen described. Human ST3GAL1 shares 85% identity with mouse ST3GAL1. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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Detection of Human ST3 beta -Gal alpha -2,3-Sialyltransferase 1/ST3GAL1 by Western Blot. Western blot shows lysates of human placenta. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human ST3 beta -Gal alpha -2,3-Sialyltransferase 1/ST3GAL1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6905) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for ST3 beta -Gal alpha -2,3-Sialyltransferase 1/ ST3GAL1 at approximately 45 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1. |
