Human IRAK3 Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human IRAK3 Affinity Purified Polyclonal Ab (25 UG)

货号： AF6264-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF6264-SP
别名	ASRT5; EC 2.7.11.1; FLJ13601; IL-1 receptor-associated kinase M; interleukin-1 receptor-associated kinase 3; IRAK-3; IRAKM; IRAK-M
全称	Interleukin-1 Receptor-Associated Kinase 3
反应种属	Human
应用	Western Blot(1 µg/mL)
目标/特异性	Detects human IRAK3 in Western blots.
使用方法	Western Blot: 1 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	11213 (Human); 73914 (Mouse); 314870 (Rat)
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human IRAK3 aa 1-596 Accession # Q9Y616
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	IL-1 receptor-associated kinases (IRAKs) are serine/threonine kinases that help mediate signaling from Toll-like receptor (TLR) and IL-1 receptor family members. Four human IRAKs have been identified: IRAK1, IRAK2, IRAK-M, and IRAK4. All IRAKs are multidomain proteins, containing a conserved N-terminal death domain as well as a central kinase domain that is only active in IRAK1 and IRAK4. IRAK4 mutations have been described in patients with recurrent bacterial infections and poor inflammatory responses.
运输条件	Blue Ice
存放说明	4℃
参考文献	IL-1 Family Intracellular Kinases Intracellular Kinases in the Akt Pathway NOD-like Receptors and the Inflammasome TNF Superfamily Regulators Toll-Like Receptors Translation Regulation Translation Regulation by the Akt Pathway

参考图片

Detection of Human IRAK3 by Western Blot. Western blot shows lysates of EOL‑1 human acute myeloid (eosinophilic) leukemia cell line and THP‑1 human acute monocytic leukemia cell line. PVDF Membrane was probed with 1 µg/mL of Sheep Anti-Human IRAK3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6264) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for IRAK3 at approximately XXX kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group XXX.

Detection of Human IRAK3 by Western Blot. Western blot shows recombinant human IRAK1, recombinant human IRAK2, recombinant human IRAK3, and recombinant human IRAK4 (2 ng/lane). PVDF Membrane was probed with 1 µg/mL of Sheep Anti-Human IRAK3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6264) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group XXX.