Human TFCP2L1 Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human TFCP2L1 Affinity Purified Polyclonal Ab (25 UG)

货号： AF5726-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF5726-SP
别名	CRTR1; CRTR1CRTR-1; LBP9; LBP-9; LBP9CP2-related transcriptional repressor 1; transcription factor CP2-like 1; transcription factor CP2-like protein 1; Transcription factor LBP-9
全称	Transcription factor CP2-like 1
反应种属	Human
应用	Western Blot(1 µg/mL)
目标/特异性	Detects human TFCP2L1 in direct ELISAs and Western blots.
使用方法	Western Blot: 1 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	29842 (Human); 81879 (Mouse); 304741 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Trim33 regulates early maturation of mouse embryoid bodies in vitro Authors: S Rajderkar, C Panaretos, V Kaartinen Biochem Biophys Rep, 2017;12(0):185-192. Species: Mouse Sample Type: Tissue Lysates Application: WB alpha-Intercalated cells defend the urinary system from bacterial infection. Authors: Paragas N, Kulkarni R, Werth M, Schmidt-Ott K, Forster C, Deng R, Zhang Q, Singer E, Klose A, Shen T, Francis K, Ray S, Vijayakumar S, Seward S, Bovino M, Xu K, Takabe Y, Amaral F, Mohan S, Wax R, Corbin K, Sanna-Cherchi S, Mori K, Johnson L, Nickolas T, DAgati V, Lin C, Qiu A, Al-Awqati Q, Ratner A, Barasch J J Clin Invest, 2014;124(7):2963-76. Species: Mouse Sample Type: Whole Cells Application: ICC
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human TFCP2L1 Met1-Lys180 Accession # Q9NZI6
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	TFCP2L1 (Transcription factor CP2‑like protein # 1; also LBP‑9) is a 54 kDa (predicted) member of the CP2 subfamily, grh/CP2 family of proteins. It is expressed in placental synctiotrophoblast cells, and regulates the production of CYP11A1/P450scc. P450scc is a cholesterol cleavage enzyme that generates pregnenolone, a necessary intermediate in the formation of progesterone. TFCP2L1 both positively and negatively regulates P450scc synthesis through homodimerization and heterodimerization with LBP‑1b. Human TFCP2L1 is 479 amino acids (aa) in length. It contains a transcriptional repressor region (aa 100‑200) and a dimerization domain (aa 300‑479). There is one splice variant that shows a deletion of aa 400‑464. Human TFCP2L1 is 73% aa identical to human TFCP2, and 93% aa identical to mouse CRTR‑1, a closely related molecule that may not represent the actual mouse ortholog to TFCP2L1.
运输条件	Blue Ice
存放说明	4℃

参考图片

Detection of Human TFCP2L1 by Western Blot. Western blot shows lysates of human placental tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human TFCP2L1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5726) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for TFCP2L1 at approximately 54 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.