Human PEDF R/PNPLA2 Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human PEDF R/PNPLA2 Affinity Purified Polyclonal Ab (25 UG)

货号： AF5387-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF5387-SP
别名	Adipose triglyceride lipase; ATGL; ATGL1110001C14Rik; Calcium-independent phospholipase A2; Desnutrin; EC 3.1.1.3; FP17548; IPLA2-zeta; patatin-like phospholipase domain containing 2; patatin-like phospholipase domain-containing protein 2; patatin-like phospholipase domain-containing protein 2-like; PEDF-R; Pigment epithelium-derived factor; PNPLA2; Transport-secretion protein 2; transport-secretion protein 2.2; triglyceride hydrolase; TTS2; TTS2.2; TTS-2.2; TTS2DKFZp667M109
全称	Pigment Epithelium-derived Factor Receptor/Patatin-like Phospholipase Domain-containing Protein 2
反应种属	Human
应用	Immunohistochemistry(5-15 µg/mL)
目标/特异性	Detects human PEDF R/PNPLA2 in direct ELISAs. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse PNPLA2 is observed.
使用方法	Immunohistochemistry: 5-15 µg/mL
来源	Sterile PBS to a final concentration of 0.2 mg/mL.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	57104 (Human); 66853 (Mouse); 361676 (Rat)
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human PEDF R/PNPLA2 Val162-Thr332 Accession # Q96AD5
生物活性	Human
标记	Unconjugated
溶解方法	Sterile PBS to a final concentration of 0.2 mg/mL.
背景	PEDF R (Pigment epithelium derived factor receptor; also ATGL, PNPLA2 and desnutrin) is a 55-60 kDa member of the PNPLA family of proteins. It is expressed in adipocytes, hepatocytes, skeletal muscle, and pigment epithelium. PEDF R specifically hydrolyses triglycerides, releasing long-chain fatty acids. Human PEDF R is described as being a 504 amino acid (aa) type II transmembrane (TM) protein. Its TM segment is stated to span aa 9-29. It also contains a palatin domain (aa 10-179) with a conserved GxSxG enzymatic motif. There is one potential isoform variant that shows a deletion of aa 2-62. Over aa 162-332, human PEDF R shares 85% aa identity with mouse PEDF R.
运输条件	Blue Ice
存放说明	4℃
参考文献	Adipocytokines Diabetes ICC / IHC Images: PEDF R/PNPLA2 Lipid Metabolism Enzymes

参考图片

PEDF R/PNPLA2 in Human Heart.

PEDF R/PNPLA2 was detected in immersion fixed paraffin-embedded sections of human heart using Goat Anti-Human PEDF R/
PNPLA2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5387) at 10 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to the sarcolemma of cardiomyocytes. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.