| 货号 | AF5116-SP |
| 别名 | CHI3L2; chitinase 3-like 2; chitinase-3-like protein 2; Chondrocyte protein 39; YKL39; YKL-39YKL39 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human Chitinase 3-like 2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human CHIT-1 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 1117 (Human) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human Chitinase 3-like 2 Tyr27-Leu390 Accession # Q15782 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Chitinase 3-like 2 (CHI3L2), also called chrondrocyte protein 39 or YKL-39, is a 39 kDa potentially glycosylated protein belonging to the family of chitinase-like lectins. These proteins are structurally related to the glycosylhydrolase family 18, but lack enzymatic activity. It is secreted by synovial fibroblasts, chondrocytes, and TGF beta/IL-4-stimulated monocyte-derived macrophages. CHI3L2 expression in synovium correlates with osteoarthritic cartilage degeneration, and is a potential biomarker for osteoarthritis. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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