Human IKK beta Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human IKK beta Affinity Purified Polyclonal Ab (25 UG)

货号： AF4535-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF4535-SP
别名	EC 2.7.11; EC 2.7.11.10; I-kappa-B kinase 2; I-kappa-B-kinase beta; IkBKB; IKK2; IKK2FLJ38368; IKK-B; IKK-betaFLJ36218; IKKBFLJ40509; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; NFKBIKBFLJ33771; Nuclear factor NF-kappa-B inhibitor kinase beta
全称	IkB Kinase beta
反应种属	Human
应用	Western Blot(1 µg/mL)
目标/特异性	Detects endogenous human IKK beta in Western blots. In Western blots, this antibody does not cross-react with recombinant human IKK alpha, IKK gamma, or IKK epsilon.
使用方法	Western Blot: 1 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3551 (Human); 16150 (Mouse); 84351 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages. Authors: Awuh J, Haug M, Mildenberger J, Marstad A, Do C, Louet C, Stenvik J, Steigedal M, Damas J, Halaas O, Flo T Proc Natl Acad Sci U S A, 2015;112(31):E4272-80. Species: Human Sample Type: Cell Lysates Application: IP
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human IKK beta Gly374-Ser756 Accession # O14920
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	I kappa B kinase beta (IKK beta ) is also known as IKBKB and IKK2. The classical active IKK complex, composed of IKK alpha, IKK beta, and two forms of processed IKK gamma, phosphorylates and inactivates I kappa B, resulting in the release and nuclear translocation of active NF-kappa B. Like IKK alpha, IKK beta contains kinase, leucine zipper, and helix‑loop‑helix domains. NF-kappa B-inducing kinase (NIK) phosphorylates and activates IKK alpha /IKK beta heterodimers.
运输条件	Blue Ice
存放说明	4℃
参考文献	Chemokine Receptor Intracellular Signaling C-type Lectin Receptors IL-1 Family IL-17 Family Intracellular Factors in Inflammation Intracellular Kinases Intracellular Kinases in the Akt Pathway Natural Killer T (NKT) Cells NFkB Pathway NOD-like Receptors and the Inflammasome Notch Pathway PDGF Family RIG-I-like Receptors Stem Cell Transcription Factor Regulators TNF Superfamily Regulators Toll-Like Receptors Transcriptional Co-Activators

参考图片

Detection of Human IKK beta by Western Blot. Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line, Raji human Burkitts lymphoma cell line, and Daudi human Burkitts lymphoma cell line. PVDF membrane was probed with 1 µg/mL of Human IKK beta Antigen Affinity‑purified Polyclonal Antibody (Catalog # AF4535) followed by HRP‑conjugated Anti‑Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for IKK beta at approximately 87 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.