Human FoxP1 Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human FoxP1 Affinity Purified Polyclonal Ab (25 UG)

货号： AF4534-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF4534-SP
别名	FLJ23741; fork head-related protein like B; forkhead box P1; forkhead box protein P1; glutamine-rich factor 1; hFKH1B; HSPC215; MGC12942; MGC88572; MGC99551; QRF1; QRF112CC4
全称	Forkhead Box P1
反应种属	Human
应用	Western Blot(1 µg/mL)
目标/特异性	Detects human FoxP1 in Western blots.
使用方法	Western Blot: 1 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	27086 (Human); 108655 (Mouse); 297480 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development J Cell Sci, 2016;0(0):. Species: Mouse Sample Type: Whole Tissue Application: IHC Frozen Fasciculation and Guidance of Spinal Motor Axons in the Absence of FGFR2 Signaling. Authors: Huettl RE, Haehl T, Huber AB PLoS ONE, 2012;7(7):e41095. Species: Mouse Sample Type: Whole Tissue Application: IHC Frozen Npn-1 contributes to axon-axon interactions that differentially control sensory and motor innervation of the limb. Authors: Huettl RE, Soellner H, Bianchi E, Novitch BG, Huber AB PLoS Biol., 2011;9(2):e1001020. Species: Mouse Sample Type: Whole Tissue Application: IHC Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development. Neuroscience, 2010;165(1):116-29. Species: Mouse Sample Type: Whole Tissue Application: IHC Frozen
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human FoxP1 Leu231-Gly420 Accession # Q9H334
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	Forkhead Box P1 (FOXP1) is a member of the FOX family of transcription factors. FoxP1 has been implicated in cardiac, lung, and lymphocyte development. FoxP1 knock out mice die at embryonic day 14.5 due to heart valve and outflow tract abnormalities. FoxP1 contains both a DNA binding domain as well as protein-protein interaction domains. FoxP1 can homo or heterodimeize with FoxP2 and FoxP4, with dimerization necessary for DNA binding. FoxP1 shows both oncogenic and tumor suppressive characteristics. Overexpression in lymphomas leads to poor prognosis, whereas, loss of FoxP1 in breast cancer also implicates a poor prognosis.
运输条件	Blue Ice
存放说明	4℃
参考文献	B Cell Development and Differentiation Forkhead Domain Transcription Factors ICC / IHC Images: FoxP1

参考图片

Detection of Human FoxP1 by Western Blot. Western blot shows lysates of Daudi human Burkitts lymphoma cell line. Gels were loaded with 30 μg of whole cell lysate (WCL), 20 μg of cytoplasmic (Cyto), and 10 μg of nuclear extracts (Nuc). PVDF membrane was probed with 1 µg/mL Goat Anti-Human FoxP1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4534) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band for FoxP1 was detected at approximately 82 - 90 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.