| 货号 | AF4336-SP |
| 别名 | CAP; CAPMGC111370; Cytoplasmic antiproteinase; deafness, autosomal recessive 91; DFNB91; Peptidase inhibitor 6; PI6; PI-6; PI6MSTP057; Placental thrombin inhibitor; protease inhibitor 6 (placental thrombin inhibitor); PTI; PTIDKFZp686I04222; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6; serpin B6; serpin peptidase inhibitor, clade B (ovalbumin), member 6; SPI3 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human Serpin B6 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross‑reactivity with recombinant human (rh) Serpin B8 and rhSerpin B9 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 5269 (Human); 20719 (Mouse); 291085 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Serpin B6 Asp2-Pro376 Accession # P35237 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Serpin B6 (serine protease inhibitor-clade B#6; also placental thrombin inhibitor) is a 42 kDa, cytosolic member of the ovalbumin (clade B)-subfamily, Serpin superfamily of protease inhibitors. It is produced by multiple cell types (keratinocytes; monocytes; mast cells), and shows inhibitory activity towards thrombin, plasmin and chymotrypsin. Human Serpin B6 is 376 amino acids (aa) in length. An active inhibitor site lies between Glu327 and Met338. Multiple potential isoforms exist. One shows a 28 aa substitution for the N-terminal 191 amino acids. Three others have alternate start sites that vary from 14‑33 aa’s upstream of the standard start site. Human Serpin B6 shares 76% aa identity with mouse Serpin B6. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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