货号 | AF4100-SP |
别名 | dipeptidyl peptidase 10; Dipeptidyl peptidase IV-related protein 3; dipeptidyl peptidase like protein 2; Dipeptidyl peptidase X; Dipeptidyl peptidase-like protein 2; dipeptidyl-peptidase 10 (non-functional); dipeptidyl-peptidase 10; DPL2; DPP X; DPPY; DPRP3; DPRP-3; DPRP3dipeptidylpeptidase 10; inactive dipeptidyl peptidase 10; KIAA1492 | 全称 | Dipeptidyl-peptidase 10 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human DPP10 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross‑reactivity with recombinant human (rh) DPP6 and rhDPP4 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 57628 (Human); 269109 (Mouse); 363972 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human DPP10 Leu56-Glu796 (Pro340Ala) Accession # NP_065919 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | DPP10 (dipeptidyl peptidase 10; also DPPY, DPRP3 and DPL2) is a 91‑97 kDa member of the peptidase S9B family. It is a type II transmembrane glycoprotein principally expressed in neurons and T cells. Although it is a peptidase member, it has no catalytic activity. Instead, it assists in the membrane trafficking and functioning of Kv4 K+ channels. Human DPP10 is 796 amino acids (aa) in length. It contains a 34 aa cytoplasmic N-terminus and a 741 aa extracellular domain (ECD) (aa 56‑796). Three potential isoforms exist, all involving aa substitutions limited to the first 20 amino acids. The ECD of human DPP10 shares 89% aa sequence identity with mouse DPP10 ECD. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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