| 货号 | AF4095-SP |
| 别名 | 51 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; EC 5.2.1.8; FK506 binding protein 4, 59kDa; FK506-binding protein 4 (59kD); FK506-binding protein 4; FKBP4; FKBP-4; FKBP51; FKBP-52; FKBP52T-cell FK506-binding protein, 59kD; FKBP59; FKBP5952 kDa FK506-binding protein; HBI; HSP binding immunophilin; Hsp56; HSP-binding immunophilin; Immunophilin FKBP52; p52; p59; peptidyl-prolyl cis-trans isomerase FKBP4; peptidylprolyl cis-trans isomerase; PPIase FKBP4; PPIase; rotamase | 全称 | 52 kDa FK506 Binding Protein |
| 反应种属 | Human/Mouse/Rat |
| 应用 | Western Blot(0.3 µg/mL) |
| 目标/特异性 | Detects endogenous human, mouse and rat FKBP52 in Western blots. In Western blots, this antibody does not cross-react with recombinant human FKBP12, FKBP13, FKBP38 or FKBP51. |
| 使用方法 | Western Blot: 0.3 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 2288 (Human); 14228 (Mouse); 260321 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant human FKBP52 Met1-Ala459 Accession # Q02790 |
| 生物活性 | Human, Mouse, Rat |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | FK506 binding protein, 52 kDa molecular weight (FKBP52), also called FKBP4, is a peptidyl-prolyl isomerase that catalyzes the transition between cis-andtrans- proline residues critical for proper folding of proteins. It associates with HSP90 complexes that are critical for the proper folding of steroid receptors. FKBP52 knockout mice have abnormal reproductive organ development due to disruption of androgen receptor folding. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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Detection of Human/Mouse/Rat FKBP52 by Western Blot. Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line. PVDF membrane was probed with 0.3 µg/mL of Human/Mouse/Rat FKBP52 Antigen Affinity‑purified Polyclonal Antibody (Catalog # AF4095) followed by HRP-conjugated Anti‑Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for FKBP52 at approximately 52 kDa (as indicated). This experiment was conducted using Immunoblot Buffer Group 2. |
