货号 | AF3889-SP |
别名 | Breast tumor autoantigen; Crp3; Etohi4; LIM domain only 4; LIM domain only protein 4; LIM domain transcription factor LMO4; LMO-4 | 全称 | LIM Domain Only 4 |
反应种属 | Human/Mouse |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human and mouse LMO4 in direct ELISAs and Western blots. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 8543 (Human); 16911 (Mouse); 362051 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant human LMO4 Met1-Cys165 Accession # P61968 |
生物活性 | Human, Mouse |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | LMO4 is a 18‑20 kDa member of the LIM-only (LMO) subfamily of LIM domain-containing transcription factors. The 165 amino acid human LMO4 comprises a trans‑activating Pro-rich N-terminus, two LIM domains, and a LIM-binding C-terminus. The LIM domain is a conserved cysteine-rich structure containing two tandemly repeated zinc fingers involved in protein-protein interaction. LIMs are found in a variety of proteins known to have critical functions in cell-fate specification and differentiation. LMO4 is both nuclear and cytoplasmic. LMO4 is overexpressed in most primary breast carcinomas. Human and mouse LMO4 protein sequences are 100% identical. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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