| 货号 | AF3749-SP |
| 别名 | plexin B1; PLXN5; PLXNB1; SEP; Transmembrane Protein SEP |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL) |
| 目标/特异性 | Detects human Plexin B1 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human Plexin B3 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 5364 (Human); 235611 (Mouse); 316009 (Rat) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Grb2 mediates semaphorin-4D-dependent RhoA inactivation. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant human Plexin B1 Leu35-Val150 Accession # O43157 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Plexin B1 is a type I transmembrane protein that belongs to the Plexinfamily of semaphorin receptors. It is derived from a single peptidethat undergoes proteolytic processing in its extracellular domain toform the non-covalently-linked heterodimer of the extracellular alpha subunit and the transmembrane beta subunit. Human Plexin B1 extracellular alpha subunit shares homology with semaphorins, HGF receptor and MSPreceptor and contains a sema domain and three IPT/TIG domains. Itfunctions as a receptor for semaphorin 4D/CD100. Multiple spliceisoforms of Plexin B1 have been reported. Within the region used asimmunogen, human Plexin B1 shares 90% and 97% amino acid sequencehomology with mouse and canine Plexin B1, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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