货号 | AF3679-SP |
别名 | LERN3; LERN3FLJ31810; leucine rich repeat and Ig domain containing 2; leucine-rich repeat and immunoglobulin-like domain-containing nogoreceptor-interacting protein 2; Leucine-rich repeat neuronal protein 3; Leucine-rich repeat neuronal protein 6C; LRRN6C; LRRN6Cleucine rich repeat neuronal 6C | 全称 | Leucine-rich Repeat And Ig Domain Containing Nogo Receptor-Interacting Protein 2 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) Immunocytochemistry(5-15 µg/mL) |
目标/特异性 | Detects human LINGO-2 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human LINGO‑1 is observed. |
使用方法 | Western Blot: 0.1 µg/mL Immunocytochemistry: 5-15 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 158038 (Human); 242384 (Mouse); 313156 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human LINGO-2 Cys28-Leu542 Accession # Q7L985 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | LINGO-2, also known as Leucine-rich repeat neuronal 6C (LRRN6C), is atype I transmembrane protein in the neuronal leucine-rich repeatfamily. These proteins have a signal peptide, 12 extracellularleucine-rich repeats flanked by N-terminal and C-terminal cysteine-richsequences, an immunoglobulin-like domain, a transmembrane domain and ashort cytoplasmic tail. Human LINGO-2 is a 606 amino acid protein withunknown functions. It is highly conserved, sharing 99% and 98% aasequence identity with canine and mouse LINGO-2, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
|