Human/Mouse BLIMP1 Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human/Mouse BLIMP1 Affinity Purified Polyclonal Ab (25 UG)

货号： AF3608-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF3608-SP
别名	Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP-1; BLIMP1MGC118925; B-lymphocyte-induced maturation protein 1; MGC118922; MGC118923; Positive regulatory domain I-binding factor 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PRDI-BF1MGC118924; PRDI-binding factor 1; PRDI-binding factor-1; PRDM1; PR-domain zinc finger protein 1; ZNFPR1A1
全称	B Lymphocyte Induced Maturation Protein
反应种属	Human/Mouse
应用	Western Blot(0.1 µg/mL)
目标/特异性	Detects human and mouse BLIMP1/PRDM1 in direct ELISAs and Western blots.
使用方法	Western Blot: 1 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	639 (Human); 12142 (Mouse); 309871 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. A role for Lin28 in primordial germ-cell development and germ-cell malignancy. Authors: West JA, Viswanathan SR, Yabuuchi A, Cunniff K, Takeuchi A, Park IH, Sero JE, Zhu H, Perez-Atayde A, Frazier AL, Surani MA, Daley GQ Nature, 2009;460(7257):909-13. Species: Mouse Sample Type: Cell Lysates Application: WB
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human BLIMP1/PRDM1 Leu687-Pro789 Accession # AAO45623
生物活性	Human, Mouse
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	BLIMP-1 is a 97 kDa multidomain transcription repressor that has a SET domain in its N-terminal region and four C2H2-type zinc fingers in its C-terminal regions. It promotes terminal differentiation of B cells into plasma cells and also has an important role in primordial germ cell specification. An alternative splice variant that lacks 101 N-terminal amino acid (aa) residues of full-length BLIMP1 has been reported. Over the region used as immunogen, human and mouse BLIMP1 share 89% aa sequence identity.
运输条件	Blue Ice
存放说明	4℃
参考文献	B Cell Development and Differentiation B Cell Markers Cancer Stem Cell Transcription Factors ICC / IHC Images: BLIMP1/PRDM1 IL-10/Interferon Family Primordial and Mature Germ Cells Signaling Molecules and Transcriptional Regulators of Tfh Cell Differentiation Transcription Factors and Regulators

参考图片

Detection of Human BLIMP1/PRDM1 by Western Blot. Western blot shows lysates of RPMI 8226 human multiple myeloma cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse BLIMP1/PRDM1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3608) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for BLIMP1/PRDM1 at approximately 95 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.