| 货号 | AF3574-SP |
| 别名 | EC 2.7.10; EC 2.7.10.2; FYN oncogene related to SRC, FGR, YES; MGC45350; OKT3-induced calcium influx regulator; p59-Fyn; protein-tyrosine kinase fyn; Proto-oncogene c-Fyn; Proto-oncogene Syn; proto-oncogene tyrosine-protein kinase fyn; SLK; SLKc-syn protooncogene; src/yes-related novel; Src-like kinase; SYN; tyrosine kinase p59fyn(T); tyrosine-protein kinase Fyn | 全称 | FYN oncogene related to SRC, FGR, YES |
| 反应种属 | Human |
| 应用 | Immunocytochemistry(10-20 µg/mL) |
| 目标/特异性 | Detects human Fyn in direct ELISAs. |
| 使用方法 | Immunocytochemistry: 10-20 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 2534 (Human) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant human Fyn Met1-Gly83 Accession # P06241 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Fyn is a ubiquitously expressed member of the Src family of intracellular tyrosine kinases. Fyn activity is implicated in T cell receptor signaling, adhesion-mediated signaling, and regulation of brain function. Mice lacking fyn display various deficits, including impaired spatial memory, hypomyelination, and uncoordinated hippocampal structure, suggesting that Fyn is involved in multiple neural signaling pathways. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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Fyn in MOLT‑4 Human Cell Line. Fyn was detected in immersion fixed MOLT‑4 human acute lymphoblastic leukemia cell line using Goat Anti-Human Fyn Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3574) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips. |
