货号 | AF3494-SP |
别名 | DDPAC; FLJ31424; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; MAPT; MGC138549; microtubule-associated protein tau; MSTD; MSTDMAPTL; MTBT1; MTBT1Neurofibrillary tangle protein; MTBT2; Neurofibrillary tangle protein; PHF-tau; PPND; tau; TAUPaired helical filament-tau | 全称 | Microtubule-Associated Protein Tau |
应用 | Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL) |
目标/特异性 | Detects human Tau in direct ELISAs and Western blots. |
使用方法 | Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 4137 (Human); 17762 (Mouse); 29477 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant human Tau Gln624-Gln756 Accession # P10636 |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Tau is a microtubule-associated protein primarily expressed in neurons.It can associate with microtubules through the carboxy-terminal domainsand with the plasma membrane through the amino-terminal projectiondomain. Tau has a role as a stabilizer of microtubules. Abnormal Tauphosphorylation or splicing is associated with various neurologicaldisorders. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Tau in Human Alzheimers Disease Brain. Tau was detected in immersion fixed paraffin-embedded sections of human Alzheimers disease brain (cortex) using 5 µg/mL Goat Anti-Tau Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3494) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections. |