| 货号 | AF3439-SP |
| 别名 | EC 3.4.24; EC 3.4.24.15; Endopeptidase 24.15; EP24.15; MEPD_HUMAN; MP78; thimet oligopeptidase 1; thimet oligopeptidase; TOP |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL) Immunoprecipitation(25 µg/mL) |
| 目标/特异性 | Detects human Oligopeptidase/THOP1 in direct ELISAs and Western blots. In Western blots, less than 5% cross-reactivity with recombinant human Neurolysin is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL Immunoprecipitation: 25 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 7064 (Human); 50492 (Mouse); 64517 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant human Oligopeptidase/THOP1 Lys2-Cys689 Accession # P52888 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | THOP1 (Thimet Oligopeptidase), also called metalloendopeptidase 24.15, is a soluble protease that is expressed ubiquitously, with highest levels in the brain. It degrades peptides released from proteasomes and neuropeptides under 20 amino acids in length. Depending on the cell type, it can be cytosolic, nuclear, secreted or membrane-associated. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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