Human Calbindin D Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human Calbindin D Affinity Purified Polyclonal Ab (25 UG)

货号： AF3320-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF3320-SP
别名	CABP1; CABP28K; S100G
全称	Vitamin D-dependent Calcium-Binding Protein
反应种属	Human
应用	Western Blot(5 µg/mL) Immunohistochemistry(5-15 µg/mL)
目标/特异性	Detects human Calbindin D in direct ELISAs and Western blots.
使用方法	Western Blot: 5 µg/mL Immunohistochemistry: 5-15 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	795 (Human); 12309 (Mouse); 24249 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Cerebrospinal fluid calbindin D concentration as a biomarker of cerebellar disease progression in Niemann-Pick type C1 disease Authors: Allison M Bradbury J Pharmacol Exp Ther, 2016;0(0):. Species: Human Sample Type: CSF Application: ELISA detection Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing. Authors: Usoskin D, Furlan A, Islam S, Abdo H, Lonnerberg P, Lou D, Hjerling-Leffler J, Haeggstrom J, Kharchenko O, Kharchenko P, Linnarsson S, Ernfors P Nat Neurosci, 2015;18(1):145-53. Species: Mouse Sample Type: Whole Tissue Application: IHC Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra. Authors: Bifsha P, Yang J, Fisher R, Drouin J PLoS Genet, 2014;10(12):e1004863. Species: Mouse Sample Type: tissue Application: IHC Paraffin-embedded Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP. Authors: Di Salvio M, Di Giovannantonio LG, Acampora D Nat. Neurosci., 2010;13(12):1481-8. Species: Mouse Sample Type: Whole Tissue Application: IHC Paraffin-embedded
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human Calbindin D Ala2-Asn261 Accession # P05937
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	Calbindin D, also known as Calbindin 1, is a Vitamin D-dependent cytoplasmic protein in the EF-hand calcium binding protein family that includes calmodulin, parvalbumin, troponin C, and S100. Calbindin D is widely expressed and regulates calcium homeostasis. Calbindin D protects neurons from excitotoxic and apoptotic cell death by buffering excess calcium. Human, mouse, and rat Calbindin D share 98% amino acid sequence identity.
运输条件	Blue Ice
存放说明	4℃
参考文献	Adult Neurogenesis Calcium-binding Proteins and Related Molecules ICC / IHC Images: Calbindin D Parkinsons Disease Related Molecules

参考图片

Detection of Human Calbindin D by Western Blot. Western blot shows human urine and lysates of human kidney tissue. PVDF membrane was probed with 5 µg/mL of Goat Anti-Human Calbindin D Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3320) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for Calbindin D at approximately 25 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.