| 货号 | AF3319-SP |
| 别名 | KIAA1036; KIAA1036vasohibin-1; VASH; VASH1; vasohibin 1 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human Vasohibin Isoform 1 in direct ELISAs and Western blots. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 22846 (Human); 238328 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Alternative splicing of vasohibin-1 generates an inhibitor of endothelial cell proliferation, migration, and capillary tube formation. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human Vasohibin Isoform 1 Pro2-Val365 Accession # Q7L8A9 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Vasohibin is an endothelium-derived negative feedback regulator of angiogenesis. Vasohibin has no canonical signal sequence, and the full-length form is only associated with cells. When N-terminally cleaved, however, active 42 kDa and 36 kDa forms are generated that are both cell-associated and secreted. Vasohibin expression is upregulated by VEGF and FGF basic/FGF-2, but the upregulation can be modulated by IL-1, TNF-alpha or IFN-gamma. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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