Human/Mouse/Rat PLC-gamma 1 Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human/Mouse/Rat PLC-gamma 1 Affinity Purified Polyclonal Ab (25 UG)

货号： AF3288-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF3288-SP
别名	EC 3.1.4.11; gamma 1 (formerly subtype 148); monophosphatidylinositol phosphodiesterase; NCKAP3,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; phosphatidylinositol phospholipase C; phosphoinositidase C; phosphoinositide phospholipase C; Phosphoinositide phospholipase C-gamma-1; phospholipase C, gamma 1; phospholipase C-148; Phospholipase C-gamma-1; Phospholipase C-II; PLC11-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; PLC148; PLC-148; PLCG1; PLC-gamma-1; PLC-II1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; PPLCA; triphosphoinositide phosphodiesterase
全称	Phospholipase C gamma 1
反应种属	Human/Mouse/Rat
应用	Western Blot(0.5 µg/mL)
目标/特异性	Detects human, mouse, and rat PLC-gamma 1 in Western blots.
使用方法	Western Blot: 0.5 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	5335 (Human); 18803 (Mouse); 25738 (Rat)
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human PLC-gamma 1 Ser1091-Leu1290 Accession # P19174
生物活性	Human, Mouse, Rat
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	Phospholipase C gamma-1 (PLC-gamma 1) is activated by receptor tyrosine kinases in response to growth factors and hormones. Activated PLC-gamma 1 catalyzes the hydrolysis of phosphatidylinositol 4,5-biphosphate to produce the second messengers inositol 1,4,5-triphosphate (IP₃) and diacylglycerol (DAG). IP₃mobilizes the release of calcium while DAG activates protein kinase C. PLC-gamma 1 plays an important role in regulating cell proliferation and differentiation.
运输条件	Blue Ice
存放说明	4℃
参考文献	Focal Adhesions GDNF Family Lipid Metabolism Enzymes Neurotrophin/Trk Family PDGF Family Phospholipases, Small GTPases, and Other Molecules in the Akt Pathway Platelets Steroid Hormones and Bioactive Lipids VEGF Family

参考图片

Detection of Human/Mouse/Rat PLC-gamma 1 by Western Blot. Western blot shows lysates of HEK293 human embryonic kidney cell line, Balb/3T3 mouse embryonic fibroblast cell line, and Nb2‑11 rat lymphoma cell line. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human/Mouse/Rat PLC-gamma 1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3288) followed by HRP‑conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for PLC-gamma 1 at approximately 155 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.