货号 | AF3189-SP |
别名 | Cell cycle protein p38-2G4 homolog; EBP1; ErbB-3 binding protein 1; ErbB3-binding protein 1; ErbB3-binding protein Ebp1; HG4-1; p38-2G4; proliferation-associated 2G4, 38kD; proliferation-associated 2G4, 38kDa; proliferation-associated protein 2G4 | 全称 | Proliferation-Associated 2G4 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human PA2G4 in direct ELISAs and Western blots. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 5036 (Human); 18813 (Mouse); 288778 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant human PA2G4 Ser2-Asp394 Accession # Q9UQ80 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | The human PA2G4 gene encodes an intracellular protein that was also identified as Ebp 1 (ErbB3 binding protein 1). It has effects on cell cycle progression and inhibits proliferation when ectopically expressed in non-immortalized fibroblasts as well as breast cancer and prostate cancer cell lines. PA2G4 shares 56% amino acid similarity with a 42 kDa protein in the fission yeast, Schizosaccharomyces pombe, suggesting a high degree of evolutionary conservation. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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