| 货号 | AF2958-SP |
| 别名 | stanniocalcin 1; stanniocalcin-1; STC1; STC-1; STCSTC-1 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human Stanniocalcin 1/STC-1 in direct ELISAs and Western blots. In these formats, less than 1% cross‑reactivity with recombinant human STC-2 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 6781 (Human) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human Stanniocalcin 1 Thr18-Ala247 Accession # P52823 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Human STC-1 is a secreted disulfide-linked homodimeric phosphorylated glycoprotein hormone (50 kDa and higher molecular weight variants) that is related to the STC protein first discovered from corpuscles of stannius in fish. It is expressed in a wide variety of tissues and has endocrine/paracrine/autocrine functions relating to calcium and phosphate homeostasis, reproduction and development. The 230 amino acid (aa) mature STC-1 contains five intrachain disulfide and one interchain disulfide bond. Human STC-1 and STC-2 share approximately 30% aa sequence homology. STC-1 is highly homologous across species. Human STC-1 shares > 95% sequence homology with mouse, rat, and bovine STC-1. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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