货号 | AF290-SP |
别名 | CD129 antigen; CD129; IL-9 receptor; IL-9R; interleukin 9 receptor; interleukin-9 receptor | 全称 | Interleukin 9 Receptor |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human IL-9 R in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross‑reactivity with recombinant human (rh) IL-2 sR gamma, rhIL-5 sR alpha, and rhIL-6 sR is observed and 10% cross-reactivity with rhIL‑2 sR beta is observed and 5% cross‑reactivity with rhIL‑1 sRII, rhIL-4 sR, and rhIL-10 sR is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3581 (Human); 16199 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-9 R Val40-Pro270 Accession # Q01113 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | The specific high affinity functional IL-9 receptor complex consists of a ligand-specific IL-9 R( alpha ) type I transmembrane subunit and the common gamma chain that is shared with the receptors for IL-2, IL-4, IL-7 and IL-15. Both the IL-9 R subunit and the common gamma chain are members of the hematopoietin receptor superfamily. Human and mouse IL-9 receptors share 53% amino acid sequence identity, and contain 468 and 533 amino acids, respectively. As a result of alternative splicing, cDNA clones encoding isoforms of IL-9 R, including a putative soluble form, have also been identified. Cells known to express IL-9 R include T cells, neutrophils, mast cells and macrophages. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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