| 货号 | AF2866-SP |
| 别名 | 2-21; C21orf11; C21orf76PANDER; chromosome 21 open reading frame 11; Cytokine-like protein 2-21; D21M16SJHU19e; family with sequence similarity 3, member B; ORF9; pancreatic derived factor; Pancreatic-derived factor; PANDER; PRED44 | 全称 | Family With Sequence Similarity 3, Member B |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human FAM3B in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 35% cross‑reactivity with recombinant mouse FAM3B is observed and less than 5% cross-reactivity with recombinant human FAM3C is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 54097 (Human) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human FAM3B isoform B Glu30-Ser235 Accession # P58499 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Members of the FAM3 family were identified based on structural, but not sequence, homology to short chain cytokines including IL-2, IL-4 and GM-CSF. FAM3 proteins are four helix bundle cytokines with four conserved cysteines in all members (FAM3A-D). FAM3B (also known as PANDER, for pancreatic derived factor) is highly expressed in alpha and beta cells of the pancreas and is being investigated as a potential contributor to beta cell death and development of type I diabetes. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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