Human SOX10 Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

产品中心

当前位置：首页>产品中心

Human SOX10 Affinity Purified Polyclonal Ab (25 UG)

货号： AF2864-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF2864-SP
别名	DOM; MGC15649; PCWH; SRY (sex determining region Y)-box 10; SRY-related HMG-box gene 10; transcription factor SOX-10; WS4; WS4C; WS4mouse, human homolog of
全称	Transcription Factor SOX10
反应种属	Human
应用	Western Blot(0.1 µg/mL) Immunocytochemistry(5-15 µg/mL)
目标/特异性	Detects human SOX10 in direct ELISAs and Western blots. In direct ELISAs, less than 2% cross-reactivity with recombinant human (rh) SOX2, rhSOX7 and rhSOX17 is observed.
使用方法	Western Blot: 0.1 µg/mL Immunocytochemistry: 5-15 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	6663 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Elevated Levels of SOX10 in Serum from Vitiligo and Melanoma Patients, Analyzed by Proximity Ligation Assay Authors: A Blokzijl, LE Chen, SM Gustafsdot, J Vuu, G Ullenhag, O Kämpe, U Landegren, M Kamali-Mog, H Hedstrand PLoS ONE, 2016;11(4):e0154214. Species: Human Sample Type: Serum Application: Proximity Ligation Assay YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells Authors: Yannick Poitelon Nat Neurosci, 2016;0(0):. Species: Rat Sample Type: Tissue Homogenates Application: IP Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo. Authors: Najm F, Madhavan M, Zaremba A, Shick E, Karl R, Factor D, Miller T, Nevin Z, Kantor C, Sargent A, Quick K, Schlatzer D, Tang H, Papoian R, Brimacombe K, Shen M, Boxer M, Jadhav A, Robinson A, Podojil J, Miller S, Miller R, Tesar P Nature, 2015;522(7555):216-20. Species: Human Sample Type: Whole Cells Application: IHC Not Specified Double minute amplification of mutant PDGF receptor alpha in a mouse glioma model. Authors: Zou H, Feng R, Huang Y, Tripodi J, Najfeld V, Tsankova N, Jahanshahi M, Olson L, Soriano P, Friedel R Sci Rep, 2015;5(0):8468. Species: Mouse Sample Type: Whole Tissue Application: IHC - Not specified Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad. Authors: Nagoshi N, Shibata S, Kubota Y, Nakamura M, Nagai Y, Satoh E, Morikawa S, Okada Y, Mabuchi Y, Katoh H, Okada S, Fukuda K, Suda T, Matsuzaki Y, Toyama Y, Okano H Cell Stem Cell, 2008;2(0):392-403. Species: Mouse Sample Type: Whole Cells Application: ICC
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human SOX10 Met1-Ala118 Accession # P56693
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	SOX10 belongs to the SOX family of transcription factors with diverseroles during development. In the central nervous system (CNS), SOX10 isrequired for the terminal differentiation of oligodendrocytes andmyelination. In the peripheral nervous system, SOX10 maintainspluripotency of neural crest stem cells and suppresses neuronaldifferentiation.
运输条件	Blue Ice
存放说明	4℃
参考文献	Glial Lineage Markers High Mobility Group (HMG) Transcription Factors Neural Crest Cell Markers

参考图片

SOX10 in BG01V Human Embryonic Stem Cells. SOX10 was detected in immersion fixed BG01V human embryonic stem cells differentiated to neural crest stem cells using Goat Anti-Human SOX10 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2864) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counterstained with DAPI (blue). Specific staining was localized to nuclei. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.