货号 | AF2778-SP |
别名 | 35 kDa dystrophin-associated glycoprotein; 35DAG; 35kD dystrophin-associated glycoprotein; CMD1L; CMD1LSG-delta; DAGD; delta-sarcoglycan; delta-SG; dystrophin associated glycoprotein, delta sarcoglycan; LGMD2F; MGC22567; placental delta sarcoglycan; sarcoglycan, delta (35kD dystrophin-associated glycoprotein); sarcoglycan, delta (35kDa dystrophin-associated glycoprotein); SGCD; SGCDP; SGD |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL) |
目标/特异性 | Detects human δ-Sarcoglycan in direct ELISAs and Western blots. |
使用方法 | Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 6444 (Human) |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant human δ-Sarcoglycan isoform 1 Met1-Glu232 Accession # Q92629 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Delta-sarcoglycan is one of six known sarcoglycans, which are type I ( alpha - and epsilon -) or type II ( beta -, gamma -, δ- or zeta -) transmembrane glycoproteins. Sarcoglycans associate in different combinations in a tissue-specific manner, to form heterotetrameric, pentameric and hexameric membrane glycoprotein complexes (SGC). SGC interacts laterally with the dystroglycan complex, and both complexes are components of the dystrophin-associated glycoprotein complex (DGC), which forms a link between the cytoskeleton and the extracellular matrix. Mutations in sarcoglycans are associated with recessive autosomally inherited muscular dystrophy. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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