| 货号 | AF2776-SP |
| 别名 | NgR2; NgRH1; reticulon 4 receptor-like 2; RTN4RL2 | 全称 | Nogo-66 Receptor-related Protein 2/Nogo-66 Receptor Homolog 1/Reticulon-4 Receptor-like 2 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human NgR2/NgRH1 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross‑reactivity with recombinant human (rh) NgR and rhNgRH2 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 349667 (Human) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human NgR2/NgRH1 Ala28-Leu401 Accession # Q86UN3 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | NgR2, also known as reticulon 4 receptor-like 2 and NgR2, is a 60 kDaglycosylphosphatidylinositol-anchored protein that is expressedprimarily in the brain. It contains eight leucine-rich repeats that areflanked by cysteine-rich sequences at both the N- as well as theC-terminus. Membrane-anchored NgR2 can be solubilized through theaction of phospholipase or an unidentified MT-MMP to generate a 46 kDasoluble receptor. Mature human NgR2 shares 48% aa sequence identitywith human NgRH2. It also shares 96% aa sequence identity with mouseand rat mature NgR2. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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