Human beta-Defensin 2 Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human beta-Defensin 2 Affinity Purified Polyclonal Ab (25 UG)

货号： AF2758-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF2758-SP
别名	BD-2; Beta-defensin 2; DEFB2; DEFB-2; DEFB2DEFB102; DEFB4A; DEFB4B; DEFB4beta-defensin 4A; Defensin, beta 2Skin-antimicrobial peptide 1; defensin, beta 4; defensin, beta 4A; HBD-2; SAP-1; SAP1BD-2
全称	Defensin 2 beta
反应种属	Human
应用	Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL)
目标/特异性	Detects human beta -Defensin 4/2 in direct ELISAs and Western blots.
使用方法	Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1673 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Inflammatory and antimicrobial responses to methicillin-resistant Staphylococcus aureus in an in vitro wound infection model. Authors: Haisma E, Rietveld M, de Breij A, van Dissel J, El Ghalbzouri A, Nibbering P PLoS ONE, 2013;8(12):e82800. Species: Human Sample Type: tissue Application: IHC Paraffin-embedded A Novel Organotypic Dento-Epithelial Culture Model: Effect of Fusobacterium nucleatum Biofilm on B-Defensin-2, -3, and LL-37 Expression. Authors: Gursoy UK, Pollanen M, Kononen E, Uitto VJ J. Periodontol., 2011;83(2):242-7. Species: Human Sample Type: Whole Tissue Application: IHC Paraffin-embedded
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human beta -Defensin 4/2 Gly24-Pro64 Accession # O15263
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	Human BD-2, also known as defensin beta 2 (DEFB-2), is a secreted, 41 amino acid residue anti-microbial protein belonging to the defensin family. Mature defensins are cationic proteins with three intramolecular disulfides and a characteristic triple-stranded beta -sheet. Human BD-2 expression is induced by inflammatory signals in multiple tissues, including airway epithelial cells and keratinocytes. At the amino acid sequence level, human BD-2 shares 98% and 51% homology with the proteins from rhesus monkey and rat, respectively.
运输条件	Blue Ice
存放说明	4℃
参考文献	Airway Inflammation and Remodeling Defensins and Antitumor Immunity Epithelial Cell Markers and Intracellular Molecules gamma delta T Cells ICC / IHC Images: beta-Defensin 2 Inflammatory Mediators Surface Ectodermal Cells

参考图片

beta -Defensin 4/2 in Human Lung. beta -Defensin 4/2 was detected in immersion fixed paraffin-embedded sections of human lung using Human beta -Defensin 4/2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2758) at 10 µg/mL overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of alveolar cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

beta -Defensin 4/2 in Human Kidney Array. beta -Defensin 4/2 was detected in immersion fixed paraffin-embedded sections of human kidney array using Human beta -Defensin 4/2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2758) at 10 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.