货号 | AF2710-SP |
别名 | EC-1; heparan sulfate 6-O-sulfotransferase 2 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) Immunoprecipitation(25 µg/mL) |
目标/特异性 | Detects human Heparan Sulfate 6-O-Sulfotransferase 2/HS6ST2 in direct ELISAs and Western blots. |
使用方法 | Western Blot: 0.1 µg/mL Immunoprecipitation: 25 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 90161 (Human) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human Heparan Sulfate 6-O-Sulfotransferase 2/HS6ST2 Gln179-Arg605 Accession # Q96MM7 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | HS6ST2 is a key enzyme in HS biosynthesis. There are at least threealternatively spliced forms, which include a long form (645 aa,NP_001070656), an intermediate form (605 aa, Q96MM7) with 40 aa deletedbetween Arg 316 and Asn 357 of the long form, and a short form startingat Met 147 of the intermediate form. Both the long and intermediateforms predict a type II membrane protein, consistent with its Golgilocation. The long form of human HS6ST2 shares 94% and 86% aa sequenceidentities with that of chimpanzee, dog, mouse, rat, and chicken,respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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