| 货号 | AF2609-SP |
| 别名 | Differentially expressed in cancerous and non-cancerous lung cells 1; DIL1; DIL-1; DIL1FLJ34460; DKFZp686G21139; FLJ16313; FLJ22401; MINDIN; M-SPONDIN; RG-1; SPON2; Spondin 2; spondin 2, extracellular matrix protein; spondin-2 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human Mindin in direct ELISAs and Western blots. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 10417 (Human); 100689 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Spondin-2 (SPON2), a more prostate-cancer-specific diagnostic biomarker. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human Mindin Glu32-Val331 Accession # Q9BUD6 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Mindin, also known as Spondin-2 and DIL-1 (Differentially expressed incancerous and non-cancerous lung cells 1) belongs to the F-spondinfamily of secreted extracellular matrix proteins. Family members arecharacterized by two N-terminal F-spondin domains (FS1 and FS2), and athird C-terminal thrombospondin type I repeat (TSP-1). Secreted Mindinexists as a disulfide-linked dimer that also forms higher orderoligomers. It functions as a pattern recognition receptor for microbesand an adhesion molecule for neurons. Mindin is secreted by neurons,macrophages and fibroblasts in a variety of tissues. Human Mindinshares 88% amino acid sequence homology with mouse and rat proteins. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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