货号 | AF2587-SP |
别名 | bA364G4.2; FLJ58374; KIAA0918; leucine-rich repeat-containing protein 11; LRRC11; SLIT and NTRK-like family, member 5; SLIT and NTRK-like protein 5 | 全称 | SLIT and NTRK-like Family, Member 5 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human SLITRK5 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human (rh) SLITRK2 and rhSLITRK4 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 26050 (Human); 75409 (Mouse); 306152 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human SLITRK5 Glu39-Val665 Accession # O94991 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | The SLITRK family of integral membrane proteins consists of at least 6 members (SLITRK1-6). They are named for the presence of two leucine-rich repeats (LRR) in the extracellular domain similar to those found in the Slit family, and a C-terminal domain with homology to Trk tyrosine kinase receptors. SLITRKs are expressed mainly in the brain, but may also show differential expression in other normal tissues and nervous system-derived tumors. Functionally, SLITRKs may modulate neurite outgrowth, and sequence variants of SLITRK1 have been linked to Tourettes syndrome. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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