| 货号 | AF2425-SP |
| 别名 | CD85 antigen-like family member K; CD85k antigen; CD85k; HM18; ILT3; ILT-3; ILT3CD85K; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains); LIR5; LIR5LILRB5; LIR-5subfamily B, member 4; member 4 | 全称 | Leukocyte Immunoglobulin-like Receptor, Subfamily B (with TM and ITIM Domains), Member 4 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) Flow Cytometry(2.5 µg/106cells) |
| 目标/特异性 | Detects human LILRB4/CD85k/ILT3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross‑reactivity with recombinant human (rh) ILT4 and rhILT5 is observed, and less than 5% cross-reactivity with recombinant human ILT2 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL Flow Cytometry: 2.5 µg/106cells |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 11006 (Human); 14728 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. IL-10 inhibits endothelium-dependent T cell costimulation by up-regulation of ILT3/4 in human vascular endothelial cells. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human LILRB4/CD85k/ILT3 Pro17-His257 Accession # ABM86208 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | ILT3, also known as leukocyte immunoglobulin-like receptor subfamily Bmember 4 (LILRB4) and leukocyte immunoglobulin-like receptor 5 (LIR-5),is a type I membrane protein that functions as a receptor for class IMHC antigens. It contains cytoplasmic ITIM motifs and is involved in the down-regulation of immune responses. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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