Human Endorepellin Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human Endorepellin Affinity Purified Polyclonal Ab (25 UG)

货号： AF2364-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF2364-SP
别名	basement membrane-specific heparan sulfate proteoglycan core protein; endorepellin (domain V region); heparan sulfate proteoglycan 2; HSPG; HSPG2; perlecan proteoglycan; Perlecan; PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia); PRCAN; SJA; SJS; SJS1
反应种属	Human
应用	Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL)
目标/特异性	Detects human Endorepellin/Perlecan in direct ELISAs and Western blots.
使用方法	Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3339 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Type IV collagen stimulates pancreatic cancer cell proliferation, migration, and inhibits apoptosis through an autocrine loop. Authors: Ohlund D, Franklin O, Lundberg E, Lundin C, Sund M BMC Cancer, 2013;13(0):154. Species: Human Sample Type: tissue Application: IHC Frozen A fragment of the LG3 peptide of endorepellin is present in the urine of physically active mining workers: a potential marker of physical activity. Authors: Parker TJ, Sampson DL, Broszczak D PLoS ONE, 2012;7(3):e33714. Species: Human Sample Type: Urine Application: WB Endorepellin, the angiostatic module of perlecan, interacts with both the alpha2beta1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism. Authors: Goyal A, Pal N, Concannon M, Paul M, Doran M, Poluzzi C, Sekiguchi K, Whitelock JM, Neill T, Iozzo RV J. Biol. Chem., 2011;286(29):25947-62. Species: Human Sample Type: Cell Lysates Application: WB
纯化方式	Antigen Affinity-purified
免疫原	Mouse myeloma cell line NS0-derived recombinant human Endorepellin/Perlecan Arg3684-Ser4391 (Ser4003Thr) Accession # P98160
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	Endorepellin is the C-terminal domain of the heparan sulfateproteoglycan perlecan, which is a modular protein found in basementmembranes. Endorepellin has been found to be an inhibitor ofangiogenesis that blocks endothelial cell adhesion to fibronectin andtype I collagen.
运输条件	Blue Ice
存放说明	4℃
参考文献	Epithelial Cell Markers and Intracellular Molecules ICC / IHC Images: Endorepellin/Perlecan Proteoglycans Proteoglycans and Regulators Surface Ectodermal Cells

参考图片

Endorepellin/Perlecan in Human Skin. Endorepellin/Perlecan was detected in immersion fixed paraffin-embedded sections of human skin using 5 µg/mL Goat Anti-Human Endorepellin/
Perlecan Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2364) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.