Human Smad5 Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

产品中心

当前位置：首页>产品中心

Human Smad5 Affinity Purified Polyclonal Ab (25 UG)

货号： AF2250-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF2250-SP
别名	Dwfc; hSmad5; JV5-1; JV5-1DKFZp781O1323; MAD homolog 5; MAD, mothers against decapentaplegic homolog 5 (Drosophila); MADH5; MADH5mothers against decapentaplegic homolog 5; mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; Mothers against DPP homolog 5; SMA- and MAD-related protein 5; SMAD 5; SMAD family member 5DKFZp781C1895; SMAD, mothers against DPP homolog 5 (Drosophila); SMAD, mothers against DPP homolog 5; Smad5
全称	Mothers Against DPP Homolog 5
反应种属	Human
应用	Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL)
目标/特异性	Detects human Smad5 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) Smad1, rhSmad2 and rhSmad4 is observed.
使用方法	Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	4090 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis. Authors: Rai D, Kim SW, McKeller MR Proc. Natl. Acad. Sci. U.S.A., 2010;107(7):3111-6. Species: Human Sample Type: Whole Cells Application: WB
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human Smad5 Val155-Arg258 Accession # Q99717
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	Smad5 (Smad; an amalgam of the Sma gene in worm and the MAD gene infruitfly) is a transcriptional modulator that is activated by BMPreceptor kinases. Human Smad5 shares 99% amino acid sequence homologywith the mouse or rat protein.
运输条件	Blue Ice
存放说明	4℃
参考文献	Airway Inflammation and Remodeling Cancer Stem Cell Transcription Factors Epithelial Stem Cell Transcription Factors ICC / IHC Images: Smad5 Intracellular Signaling Molecules in Angiogenesis Mesenchymal Stem Cell Transcription Factors Mesenchymal to Epithelial Transition Pluripotent Stem Cell Transcription Factors Primordial and Mature Germ Cells Smad Family Smad Transcription Factors TGF-beta Family TGF-beta Superfamily Modulators Transcription Factors in the Akt Pathway

参考图片

Smad5 in Human Colon. Smad5 was detected in immersion fixed paraffin-embedded sections of human colon using 5 µg/mL Human Smad5 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2250) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of epithelial cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.