Human GAD2/GAD65 Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human GAD2/GAD65 Affinity Purified Polyclonal Ab (25 UG)

货号： AF2247-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF2247-SP
别名	EC 4.1.1; EC 4.1.1.15; GAD65; GAD-65; GAD65MGC161605; glutamate decarboxylase 2 (pancreatic islets and brain, 65kD); glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; Glutamate decarboxylase-2 (pancreas); MGC161607,65 kDa glutamic acid decarboxylase
全称	Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa)
反应种属	Human
应用	Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL)
目标/特异性	Detects human GAD2/GAD65 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human GAD1/GAD67 is observed.
使用方法	Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	2572 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Prolonged human neural stem cell maturation supports recovery in injured rodent CNS Authors: P Lu, S Ceto, Y Wang, L Graham, D Wu, H Kumamaru, E Staufenber, MH Tuszynski J. Clin. Invest., 2017;0(0):. Species: Human Sample Type: Whole Cells Application: ICC
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human GAD2/GAD65 Ala1-Ala150 Accession # Q05329
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	Glutamic acid decarboxylases (GAD), which catalyze the formation ofgamma-aminobutyric acid from L-glutamic acid, are detectable indifferent isoforms encoded by distinct genes. GAD2, also known asGAD65, is expressed in the brain and pancreatic islets. GAD2 has beenimplicated as an autoantigen in the autoimmune disease Stiff ManSyndrome and in insulin-dependent diabetes mellitus.
运输条件	Blue Ice
存放说明	4℃
参考文献	GABA Receptors Interactive Pathway: Synaptic Neurotransmission: GABAergic Inhibition Neuronal Lineage Markers Neurotransmitters, Neuroactive Molecules and Associated Enzymes

参考图片

GAD2/GAD65 in Human Dorsal Root Ganglia. GAD2/GAD65 was detected in immersion fixed paraffin-embedded sections of human dorsal root ganglia using Goat Anti-Human GAD2/GAD65 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2247) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to dorsal roots. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.