Human FCRL2/FcRH2 Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human FCRL2/FcRH2 Affinity Purified Polyclonal Ab (25 UG)

货号： AF2048-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF2048-SP
别名	CD307b antigen; CD307b; Fc receptor homolog 2; Fc receptor-like 2; FcRH2; FCRH2SPAP1B; FcRL2; FcR-like protein 2; IFGP family protein 4; IFGP4; Immunoglobulin receptor translocation-associated protein 4; immunoglobulin superfamily Fc receptor, gp42; IRTA4; IRTA4SPAP1C; SH2 domain containing phosphatase anchor protein 1; SH2 domain-containing phosphatase anchor protein 1Fc receptor-like protein 2; SPAP1; SPAP1A; SPAP1immune receptor translocation-associated protein 4
全称	Fc Receptor-like 2
反应种属	Human
应用	Western Blot(0.1 µg/mL) Flow Cytometry(2.5 µg/10⁶cells)
目标/特异性	Detects human FCRL2/FcRH2 in direct ELISAs and Western blots. In Western blots, approximately 5% cross-reactivity with recombinant human (rh) IRTA5 is observed and less than 2% cross-reactivity with rhITRA1, rhIRTA2, and rhIRTA3 is observed.
使用方法	Western Blot: 0.1 µg/mL Flow Cytometry: 2.5 µg/10⁶cells
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	79368 (Human)
纯化方式	Antigen Affinity-purified
免疫原	Mouse myeloma cell line NS0-derived recombinant human FCRL2/FcRH2 Glu15-Asp395 Accession # Q96LA5
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	Fc receptor homologs, also known as IRTA or IFGP (IgSF, FcR, gp42) proteins, are transmembrane proteins with sequence homology to classical Fc receptors. FcRH have from three to nine Ig-like domains in their extracellular region and variable combinations of cytoplasmic immunotyrosine activation or inhibitory motifs (ITAM or ITIM). FcRH function as activating or inhibitory receptors on discrete B cell populations and are involved in lymphocyte development and transformation. No ligands for these proteins have been identified.
运输条件	Blue Ice
存放说明	4℃
参考文献	B Cell Activation Fc Receptors ITIM/ITAM Immunoreceptors and Related Molecules

参考图片

Detection of FCRL2/FcRH2 in Human B Cells by Flow Cytometry. Human whole blood CD19 ⁺ B cells were stained with Goat Anti-Human FCRL2/FcRH2 Antigen Affinity‑purified Polyclonal Antibody (Catalog # AF2048) followed by Allophycocyanin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0108) and Human CD19 Phycoerythrin-conjugated Monoclonal Antibody (Catalog # FAB4867P). Quadrant markers were set based on control antibody staining (Catalog # AB‑108‑C).