| 货号 | AF1869-SP |
| 别名 | DKFZp779H1622; Histidine-proline-rich glycoprotein; histidine-rich glycoprotein; HPRGHRGP; HRG | 全称 | Histidine-rich Glycoprotein Precusor |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human HPRG in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant mouse HPRG is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3273 (Human) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human HPRG Val19-Lys525 Accession # P04196 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | HPRG (Histidine-Proline-rich Glycoprotein) is a novel member of the Cystatin superfamily of cysteine proteinase inhibitors. It is a circulating glycoprotein, 67kDa in size with multiple modules. N-terminally, there are two Cystatin-like domains that interact with the immune system. C-terminally, there is one His-Pro-rich domain that is flanked by two Pro-rich segments. The Pro-rich regions bind Plasminogen while the His-Pro module binds heparan under low pH conditions. It shows anti-angiogenic and anti-fibrinolytic activity. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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