Human Amnionless Affinity Purified Polyclonal Ab (25 UG)
货号：
AF1860-SP 基本售价：
1378.1 元 规格：
-
产品信息
概述| 货号 | AF1860-SP |
| 别名 | AMN; amnionless homolog (mouse); PRO1028; protein amnionless; UNQ513/PRO1028; visceral endoderm-specific type 1 transmembrane protein |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL)
|
| 目标/特异性 | Detects human Amnionless in direct ELISAs and Western blots. |
| 使用方法 | Western Blot: 0.1 µg/mL
|
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 81693 (Human); 93835 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human Amnionless
aa 20-368 |
| 内毒素水平 | <0.10 EU per 1 μg of the antibody by the LAL method. |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | AMN is type I transmembrane protein that is required for surface expression of the extracellular membrane-associated protein, cubilin. The two form a complex termed CUBAM in which AMN mediates endocytosis of compounds bound by cubulin. AMN is required for embryonic primitive streak formation in the mouse, and is highly expressed on adult polarized epithelia in the small intestine and kidney proximal convoluted tubules. Mutations of AMN or cubilin cause Imersund-Grasbeck syndrome, also called megaloblastic anemia-1, characterized by malabsorption of cobalamin (vitamin B12). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - BMP Family
- Epithelial Cell Markers and Intracellular Molecules
- ICC / IHC Images: Amnionless
- Renal Markers
- Surface Ectodermal Cells
|
