Human RECK Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human RECK Affinity Purified Polyclonal Ab (25 UG)

货号： AF1734-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF1734-SP
别名	hRECK; membrane-anchored glycoprotein (metastasis and invasion); reversion-inducing-cysteine-rich protein with kazal motifs; ST15; ST15reversion-inducing cysteine-rich protein with Kazal motifs; suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein withkazal motifs); suppression of tumorigenicity 5 (reversion-inducing-cysteine-rich protein withkazal motifs); Suppressor of tumorigenicity 15 protein
全称	Reversion-inducing-cysteine-rich Protein with Kazal Motifs
反应种属	Human
应用	Western Blot(1 µg/mL) Immunoprecipitation(25 µg/mL)
目标/特异性	Detects human RECK in direct ELISAs and Western blots.
使用方法	Western Blot: 1 µg/mL Immunoprecipitation: 25 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	8434 (Human); 53614 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. RECK controls breast cancer metastasis by modulating a convergent, STAT3-dependent neoangiogenic switch. Authors: Walsh, L A, Roy, D M, Reyngold, M, Giri, D, Snyder, A, Turcan, S, Badwe, C R, Lyman, J, Bromberg, J, King, T A, Chan, T A Oncogene, 2015;34(17):2189-203. Species: Human Sample Type: Cell Lysates Application: IP MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization. Authors: Vagima Y, Avigdor A, Goichberg P, Shivtiel S, Tesio M, Kalinkovich A, Golan K, Dar A, Kollet O, Petit I, Perl O, Rosenthal E, Resnick I, Hardan I, Gellman YN, Naor D, Nagler A, Lapidot T J. Clin. Invest., 2009;119(3):492-503. Species: Human Sample Type: Whole Tissue Application: IHC miR-21 plays a pivotal role in gastric cancer pathogenesis and progression. Authors: Zhang Z, Li Z, Gao C, Chen P, Chen J, Liu W, Xiao S, Lu H Lab. Invest., 2008;88(12):1358-66. Species: Human Sample Type: Cell Lysates Application: WB
纯化方式	Antigen Affinity-purified
免疫原	Mouse myeloma cell line NS0-derived recombinant human RECK Gly27-Val934 Accession # O95980
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	RECK is a GPI-anchored membrane protein that is highly expressed inmost of the human tissues and untransformed cells, but is undetectablein tumor cells. RECK can negatively regulate MMP-9, MMP-2 and MTI-MMPactivity and inhibit tumor angiogenesis and metastasis.
运输条件	Blue Ice
存放说明	4℃
参考文献	Airway Inflammation and Remodeling Metalloproteases and Regulators MMPs, TIMPs and Related Molecules

参考图片

Detection of Human RECK by Western Blot. Western blot shows lysates of human liver tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human RECK Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1734) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for RECK at approximately 130 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.