货号 | AF1698-SP |
别名 | annexin II ligand, calpactin I, light polypeptide; ANX2L; ANX2LG; CAL1LGP11,42C; Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; CLP11Ca[1]; MGC111133; p10 protein; p10; P11; protein S100-A10; S100 calcium binding protein A10 (annexin II ligand, calpactin I, lightpolypeptide (p11)); S100 calcium binding protein A10; S100 calcium-binding protein A10 (annexin II ligand, calpactin I, lightpolypeptide (p11)); S100 calcium-binding protein A10 | 全称 | S100 Calcium Binding Protein |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL) |
目标/特异性 | Detects human S100A10 in direct ELISAs and Western blots. In direct ELISAs, greater than 60% cross-reactivity with recombinant mouse S100A10 and less than 2% cross-reactivity with recombinant human S100P is observed. |
使用方法 | Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 6281 (Human); 20194 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant human S100A10 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | S100A10 is a member of the S100 family of EF hand calcium-bindingproteins. It is primarily found in mast cells as heterotetramericcomplexes (two annexin A2 subunits and two S100 A10 subunits) that arepresent intracellularly at the plasma membrane or on the extracellularcell surface. Extracellular S100A10 is a key plasminogen receptor thatplays an important role in cellular plasmin production and cellularinvasiveness. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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S100A10 in Human Kidney Cancer Tissue. S100A10 was detected in immersion fixed paraffin-embedded sections of human kidney cancer tissue using 5 µg/mL Goat Anti-Human S100A10 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1698) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections. |