Human/Mouse/Rat TOR Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Human/Mouse/Rat TOR Affinity Purified Polyclonal Ab (25 UG)

货号： AF15371-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF15371-SP
别名	EC 2.7.11.1; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FLJ44809; FRAP; FRAP1; FRAP1FKBP12-rapamycin complex-associated protein 1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); Mechanistic target of rapamycin; MTOR; RAFT1; rapamycin and FKBP12 target 1; rapamycin associated protein FRAP2; Rapamycin target protein 1; RAPT1FKBP-rapamycin associated protein; serine/threonine-protein kinase mTOR
全称	Mammalian Target of Rapamycin
反应种属	Human/Mouse/Rat
应用	Western Blot(1 µg/mL) Immunoprecipitation(2 µg/500 µg cell lysate)
目标/特异性	Detects human, mouse, and rat TOR.
使用方法	Western Blot: 1 µg/mL Immunoprecipitation: 2 µg/500 µg cell lysate
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	2475 (Human); 287871 (Rat)
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human TOR Phe1720-Ala2020 Accession # P42345
生物活性	Human, Mouse, Rat
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	The Target of Rapamycin (TOR) is a member of the PI 3-kinase-related kinase (PIKK) family. TOR is the protein target of rapamycin, an anti-rejection drug used in transplantation and promising anti-cancer agent. TOR plays a crucial role in the control of cell growth and proliferation as a downstream target of the PI 3-kinase/Akt signal transduction pathway.
运输条件	Blue Ice
存放说明	4℃
参考文献	A Novel Pathway for TOR-independent Autophagy Regulation by Akt Apoptosis Intracellular Kinases Autophagy Chemokine Receptor Intracellular Signaling Growth Hormone/IGF-I Axis ICC / IHC Images: TOR Interactive Pathway: mTOR Signaling Intracellular Kinases Intracellular Kinases in the Akt Pathway Notch Pathway Parkinsons Disease Related Molecules Positive Regulators of the Jak/STAT Pathway Regulatory T Cells (Tregs) ROS and Stress Resistance

参考图片

Detection of Human/Mouse/Rat TOR by Western Blot. Western blot shows lysates of MCF‑7 human breast cancer cell line, Balb/3T3 mouse embryonic fibroblast cell line, and NRK rat normal kidney cell line. PVDF membrane was probed with 1 µg/mL of Human/Mouse/Rat TOR Antigen Affinity-purified Polyclonal Antibody (Catalog # AF15371) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for TOR at approximately 280 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.