Phospho-Src (Ser17) Antibody
货号:
5473S 基本售价:
3980.0 元 规格:
-
产品信息
概述货号 | 5473S |
反应种属 | Human/Rat |
来源宿主 | Rabbit |
应用 | W |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells (1). Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2). |
存放说明 | -20C |
计算分子量 | 60 |
参考图片Western blot analysis of extracts from C2C12 and MCF7 cells, untreated (-) or treated with λ phosphatase (+), using Phospho-Src (Ser17) Antibody or Src (32G5) Rabbit mAb #2123. |