Phospho-Semaphorin 4B (Ser825) Antibody
货号:
5622S 基本售价:
3980.0 元 规格:
-
产品信息
概述货号 | 5622S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Rabbit |
应用 | W |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | The semaphorin family of proteins is involved in axon guidance, cell migration, angiogenesis, and immune response. Plexins and neuropilins bind with high affinity to semaphorins to mediate their functions. Semaphorins are divided into seven classes of secreted or membrane-bound proteins. Members of Class 4 semaphorins include 4A through 4G; semaphorin 4B is a membrane-associated protein (1,2). Semaphorin 4B binds to the CLCP1 receptor and regulates cell motility (3). Furthermore, semaphorin 4B, like many other semaphorins, has a PDZ domain-binding motif at the carboxy terminus that interacts with PSD95 and localizes to the post-synaptic membrane (4).The phosphorylation site at Ser825 was identified at Cell Signaling Technology using PTMScan® Technology, a proprietary proteomic method for post-translational modification site discovery (5). |
存放说明 | -20C |
计算分子量 | 105 |
参考图片Western blot analysis of extracts from MKN-45 cells, untreated or SU11274-treated (1 μM for 2 hr), using Phospho-Semaphorin 4B (Ser825) Antibody (upper) and Semaphorin 4B Antibody #3355 (lower). Western blot分析MKN-45细胞(未处理,或1uM SU11274处理2小时),使用的抗体是Phospho-Semaphorin 4B (Ser825) Antibody 兔多抗(上图)或Semaphorin 4B Antibody 兔多抗#3355(下图)。 |