Phospho-PLD1 (Ser561) Antibody
货号：
3834S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 3834S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Phospho-PLD1 (Ser561) Antibody detects endogenous levels of PLD1 only when phosphorylated at serine 561. This antibody does not cross-react with phosphorylated PLD2. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Phosphatidylcholine-specific phospholipase D (PLD) hydrolyzes phosphatidylcholine (PC) to produce choline and phosphatidic acid (PA). PA is the precursor of the second messenger, diacylglycerol (DAG). Two isoforms of PLD (PLD1 and PLD2) have been identified so far. Both are regulated by protein kinases, small GTPases and Ca2+ (1). PLD1 is phosphorylated at Ser2, Ser561 and Thr147 by PKC (2,3). Phosphorylation at Thr147 and Ser561 regulates PLD1 activity (3). |
| 存放说明 | -20C |
| 计算分子量 | 120 |
参考图片Western blot analysis of extracts from C6 cells, untreated or PMA-stimulated for the indicated times, using Phospho-PLD1 (Ser561) Antibody (upper) or PLD1 Antibody #3832 (lower). 对未处理或PMA处理适当时间的C6细胞抽提物，使用Phospho-PLD1 (Ser561)抗体（上图）或PLD1抗体#3832（下图）进行Western blot分析。 |
