Phospho-MARCKS (Ser152/156) Antibody
货号：
2741S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 2741S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Phospho-MARCKS (Ser152/156) Antibody detects endogenous levels of MARCKS only when phosphorylated at serines 152 and 156. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) is a major PKC substrate expressed in many cell types. MARCKS has been implicated in cell motility, cell adhesion, phagocytosis, membrane traffic, and mitogenesis (1). PKC phosphorylates Ser159, 163, 167, and 170 of MARCKS in response to growth factors and oxidative stress. Phosphorylation at these sites regulates the calcium/calmodulin binding and filamentous (F)-actin cross-linking activities of MARCKS (2-4). Phosphorylation by PKC also results in translocation of MARCKS from the plasma membrane to the cytoplasm (5). |
| 存放说明 | -20C |
| 计算分子量 | 75 mouse, rat. 80 human. |
参考图片Western blot analysis of extracts from NIH/3T3 and C6 cells starved for 16 hours and treated with TPA (0.2 µM) for 30 minutes. 对NIH/3T3和C6细胞饥饿处理16小时后经0.2uM TPA处理30分钟，抽提液进行Western blot分析。 |
