Phospho-Jak2 (Tyr1007/1008) Antibody
货号：
3771S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 3771S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | Phospho-Jak2 (Tyr1007/1008) Antibody detects endogenous levels of Jak2 only when phosphorylated at Tyr1007/1008. This antibody may cross-react with phospho-Jak1 and phospho-Tyk2. |
| 使用方法 | WB(1:1000)
IP (1:50) |
性能| 供应商 | CST |
| 背景 | Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3 and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats (2), Shc (3), insulin receptor substrates (4) and focal adhesion kinase (FAK) (5), typically contain SH2 or other phospho-tyrosine-binding domains. |
| 存放说明 | -20C |
| 计算分子量 | 125 |
参考图片Western blot analysis of extracts from UT7 cells, untreated or treated with GM-CSF (5 min), and BaF3 cells, untreated or treated with IL-3 (5 min), using Phospho-Jak2 (Tyr1007/1008) Antibody #3771 (upper) or total Jak2 (D2E12) XP® Rabbit mAb #3230 (lower).Western免疫印迹。用Phospho-Jak2 (Tyr1007/1008) Antibody #3771 (上图) 或 total Jak2 (D2E12) XP® Rabbit mAb #3230 (下图)研究未经处理的和经GM-CSF (5 min)处理的UT7细胞的细胞提取液和未经处理的和经IL-3 (5 min)处理的BaF3细胞的细胞提取液 。 |
