Phospho-Jak1 (Tyr1034/1035) Antibody
货号：
3331S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 3331S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Phospho-Jak1 (Tyr1022/1023) Antibody detects endogenous levels of Jak1 only when phosphorylated at tyrosines 1022/1023. This antibody may cross-react with phospho-Jak2. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3 and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats (2), Shc (3), insulin receptor substrates (4) and focal adhesion kinase (FAK) (5), typically contain SH2 or other phospho-tyrosine-binding domains. |
| 存放说明 | -20C |
| 计算分子量 | 130 |
参考图片Western blot analysis of extracts from HT-29 cells treated with IL-4 (100 ng/ml) for the indicated times, using Phospho-Jak1 (Tyr1022/1023) Antibody (upper) or Jak1 Antibody (lower).Western免疫印迹。用Phospho-Jak1 (Tyr1022/1023) Antibody (上图) 或 Jak1 Antibody (下图)研究经IL-4 (100 ng/ml) 处理一定时间的HT-29 细胞的细胞提取液。 |
