Phospho-IRF-7 (Ser471/472) Antibody
货号：
5184S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 5184S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Phospho-IRF-7 (Ser471/472) Antibody detects transfected levels of IRF-7 when phosphorylated at Ser471 and 472. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Interferon regulatory factors (IRFs) comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection (1). IRFs play an important role in pathogen defense, autoimmunity, lymphocyte development, cell growth, and susceptibility to transformation. The IRF family includes nine members: IRF-1, IRF-2, ISGF3γ/p48, IRF-3, IRF-4 (Pip/LSIRF/ICSAT), IRF-5, IRF-6, IRF-7, and IRF-8/ICSBP. All IRF proteins share homology in their amino-terminal DNA-binding domains. IRF family members regulate transcription through interactions with proteins that share similar DNA-binding motifs, such as IFN-stimulated response elements (ISRE), IFN consensus sequences (ICS) and IFN regulatory elements (IRF-E) (2). |
| 存放说明 | -20C |
| 计算分子量 | 65 |
参考图片Western blot analysis of extracts from 293T cells, mock transfected or transfected with IKKε and/or IRF-7, using Phospho-IRF-7 (Ser471/472) Antibody (upper) or IRF-7 Antibody #4920 (lower).Western免疫印迹。用Phospho-IRF-7 (Ser471/472) Antibody(上图)和IRF-7 Antibody #4920 (下图)研究未转染和转染了IKKε 和/或IRF-7的293T细胞的细胞提取液。 |
