Phospho-HS1 (Tyr397) Antibody
货号:
4507S 基本售价:
3980.0 元 规格:
-
产品信息
概述货号 | 4507S |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | Phospho-HS1 (Tyr397) Antibody detects the endogenous level of HS1 protein when phosphorylated at Tyr397. |
使用方法 | WB(1:1000) IP (1:50) |
性能供应商 | CST |
背景 | HS1 (HCLS1, LckBP1, p75) is a protein kinase substrate that is expressed only in tissues and cells of hematopoietic origin (1,2). HS1 contains four cortactin repeats and a single SH3 domain (2). This intracellular protein is phosphorylated following immune receptor activation, which promotes recruitment of HS1 to the immune synapse (3-5). Phosphorylation of HS1 is required to regulate actin dynamics and provide docking sites for many other signaling molecules, such as Vav1 and PLCγ1 (6). HS1 also plays an important role in platelet activation (7). |
存放说明 | -20C |
计算分子量 | 80 |
参考图片Western blot analysis of total extracts from Ramos cells, serum-starved for 2 hours and treated with anti-IgM antibody for 10 minutes, using Phospho-HS1 (Tyr397) Antibody (upper) or HS1 Antibody (Human Specific) #4503 (lower).Western免疫印迹。用Phospho-HS1 (Tyr397) Antibody(上图) 或 HS1 Antibody (人特异性) #4503 (下图) 研究血清饥饿2小时并经anti-IgM antibody 处理10分钟的Ramos 细胞的总细胞提取液。 |